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Safety and Efficacy of Pallidal or Subthalamic Nucleus Stimulation in Advanced PD Neurol 56:548-551, Volkmann,J.,et al, 2001 See this aricle in Pubmed Article Abstract The authors retrospectively compared 1-year results of bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN; n = 16) and internal pallidum (GPi) (n = 11) in advanced PD and found about equal improvement in "off" period moto r symptoms, dyskinesias, and fluctuations. STN stimulation reduced medication requirements by 65% and required significantly less electrical power. These advantages contrasted with need for more intensive postoperative monitoring and a higher incidence of adverse events related to levodopa withdrawal.

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(click to filter results - removes previous filter) drug withdrawal globus pallidus,stimulation L-dopa,drug interactions with and side effects of Parkinson disease Parkinson disease,surgical treatment of Parkinson disease,treatment of stimulation,deep brain

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